What is telomerase?

Publié le 2017/02/13

Telomerase is also highly expressed in pathological conditions, such as cancer, where it sustains the immortal growth of cancer cells. Healthy cells usually produce little or no telomerase and, as a consequence of this, they progressively shorten their telomeres associated with successive cycles of cell division, until they reach a critically short length which triggers cell death or an irreversible cell arrest known as replicative senescence (also known as the Hayflick limit).

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