What is telomerase?

Publié le 02/13/2017

Telomerase is also highly expressed in pathological conditions, such as cancer, where it sustains the immortal growth of cancer cells. Healthy cells usually produce little or no telomerase and, as a consequence of this, they progressively shorten their telomeres associated with successive cycles of cell division, until they reach a critically short length which triggers cell death or an irreversible cell arrest known as replicative senescence (also known as the Hayflick limit).

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